|
|
|
|
We interpret the data to mean that MS susceptility is genetically influenced,and a single dominant or even a single recessive gene is unlikely to account for this effect.The difference in concordance rates suggests that at least two or more genes are operative.These date also have important implications for the nature of the environmental effect(s) in MS susceptibility.Most monozygotic twins are discordant even after a correction for age and magnetic resonance imaging findings.This unambiguously demonstrates the powerful effect of nonheritable factors. |
|